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In the search for physics beyond the Standard Model (SM) of particle physics heavy beauty particles provide important information. The large amount of data gathered by the B factories and the LHCb experiment allows testing the SM with high precision, probing scales much higher than the reach of direct searches at the LHC. In this sense, beauty particles can serve as a Telescope in the search for new interactions and particles. But this can only be achieved by combining the data with precise and reliable theoretical predictions. Intriguingly, by studying the decays of beauty particles, we encountered instances where data and theory did not match: "puzzles". These could be the first sign of a new interaction, or just a misinterpretation of the data. In this talk, I will discuss these puzzles and the challenges and new ideas to push the theoretical precision up, to improve our understanding of particle physics and hopefully find signals of new particles.